Differential Modulation of Androgen Receptor Action by Deoxyribonucleic Acid Response Elements
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چکیده
منابع مشابه
Modulation of androgen receptor transactivation by gelsolin: a newly identified androgen receptor coregulator.
The partial agonist effect of antiandrogens has been well documented, and such effect is amplified by derived mutant androgen receptors (ARs) in prostate cancer cells. Here we report the identification of gelsolin (GSN) as an AR-associated protein. Hydroxyflutamide (HF), as well as androgens, can promote the interaction between AR and GSN in a dose-dependent manner. GSN interacts with AR DNA-bi...
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The partial agonist effect of antiandrogens has been well documented, and such effect is amplified by derived mutant androgen receptors (ARs) in prostate cancer cells. Here we report the identification of gelsolin (GSN) as an AR-associated protein. Hydroxyflutamide (HF), as well as androgens, can promote the interaction between AR and GSN in a dosedependent manner. GSN interacts with AR DNA-bin...
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ژورنال
عنوان ژورنال: Molecular Endocrinology
سال: 2003
ISSN: 0888-8809,1944-9917
DOI: 10.1210/me.2002-0379